@import"https://fonts.googleapis.com/css2?family=DM+Mono:wght@400;500&family=DM+Sans:wght@400;500;600;700&family=Space+Grotesk:wght@500;600;700&display=swap";:root{color:#19324d;background:#f5f8fb;font-family:DM Sans,Inter,ui-sans-serif,system-ui,sans-serif;font-synthesis:none;--bg: #f5f8fb;--surface: #ffffff;--surface-subtle: #eef4f7;--surface-accent: #e7f3f6;--line: #d6e1e9;--line-strong: #b9ccd9;--text: #19324d;--text-secondary: #4d667d;--muted: #72879a;--brand: #176b87;--brand-strong: #0e526a;--brand-soft: #e1f0f4;--accent: #bd762a;--accent-soft: #fff3e2;--positive: #207b70;--negative: #b04f52;--info: #5578a6;--shadow-sm: 0 2px 8px rgba(30, 65, 92, .06);--shadow-md: 0 12px 32px rgba(30, 65, 92, .09);--radius-sm: 5px;--radius-md: 9px;--radius-lg: 15px;--chart-grid: #dce6ec;--chart-label: #6c8294;--chart-effect: #207b70;--chart-rg: #bd762a;--chart-effect-area: rgba(32, 123, 112, .12);--chart-rg-area: rgba(189, 118, 42, .13)}*{box-sizing:border-box}body{margin:0;min-width:320px;background:linear-gradient(180deg,#fbfcfd 0,var(--bg) 420px)}button,input{font:inherit}button{cursor:pointer}a{color:inherit;text-decoration:none}a,button,input{-webkit-tap-highlight-color:transparent}:focus-visible{outline:3px solid rgba(23,107,135,.28);outline-offset:3px}.app-shell{min-height:100vh;display:flex;flex-direction:column}.topbar{height:76px;padding:0 clamp(20px,5vw,76px);display:flex;align-items:center;gap:34px;border-bottom:1px solid var(--line);background:#fffffff0;-webkit-backdrop-filter:blur(14px);backdrop-filter:blur(14px);position:sticky;top:0;z-index:10;box-shadow:0 1px 10px #1f3d550a}.brand{display:flex;gap:10px;align-items:center;letter-spacing:.08em;color:var(--text)}.brand-mark{display:grid;place-items:center;width:31px;height:31px;border:1.5px solid var(--brand);border-radius:7px;color:var(--brand);font-family:Space Grotesk;font-weight:700;background:var(--brand-soft)}.brand strong,.brand small{display:block}.brand strong{font-size:13px;line-height:13px}.brand small{color:var(--muted);font:9px DM Mono;letter-spacing:.16em;margin-top:3px}.main-nav{display:flex;gap:23px;align-items:center;font-size:13px;color:var(--text-secondary);flex:1}.main-nav a{padding:8px 0;border-bottom:2px solid transparent}.main-nav a:hover,.main-nav a.router-link-active{color:var(--brand);border-bottom-color:var(--brand)}.copilot-link{color:var(--accent)!important}.locale-toggle{border:1px solid var(--line-strong);border-radius:999px;padding:7px 11px;color:var(--brand);background:var(--surface);font:10px DM Mono;letter-spacing:.06em;white-space:nowrap}.locale-toggle:hover{border-color:var(--brand);background:var(--brand-soft)}.version-pill,.bounded-badge{font:10px DM Mono;letter-spacing:.08em;color:var(--brand);border:1px solid #b6d4dd;border-radius:999px;padding:8px 10px;white-space:nowrap;background:var(--brand-soft)}.menu-toggle{display:none;margin-left:auto;background:var(--surface);color:var(--brand);border:1px solid var(--line);border-radius:var(--radius-sm);padding:8px 11px}.page-wrap{width:min(1290px,calc(100% - 40px));margin:0 auto;flex:1}.site-footer{width:min(1290px,calc(100% - 40px));margin:80px auto 22px;padding-top:15px;border-top:1px solid var(--line);display:flex;justify-content:space-between;color:var(--muted);font:10px DM Mono;letter-spacing:.04em}.kicker,.eyebrow{color:var(--brand);font:11px DM Mono;letter-spacing:.15em;margin:0 0 18px}.kicker span{color:var(--accent)}h1 em,h2 em{color:var(--brand);font-style:normal}.page-header h1,.detail-hero h1,.evidence-hero h1,.copilot-page h1{font:600 clamp(36px,4vw,44px)/1.08 "Space Grotesk";letter-spacing:-.035em;margin:0 0 12px;color:var(--text)}.page-header>p:not(.kicker),.detail-hero>p,.evidence-hero p,.copilot-page>p{color:var(--text-secondary);line-height:1.7;max-width:570px;font-size:16px}.button{display:inline-flex;align-items:center;justify-content:center;gap:12px;padding:13px 18px;border:1px solid transparent;border-radius:var(--radius-sm);font-weight:700;font-size:13px;transition:background .18s,border-color .18s,transform .18s}.button:hover{transform:translateY(-1px)}.button.primary{color:#fff;background:var(--brand);box-shadow:0 4px 10px #176b8729}.button.primary:hover{background:var(--brand-strong)}.button:disabled,.text-button:disabled{cursor:wait;opacity:.52;transform:none}.button.ghost{color:var(--brand);border-color:var(--line-strong);background:var(--surface)}.button.ghost:hover{border-color:var(--brand);background:var(--brand-soft)}.button.small{padding:9px 12px;font-size:11px}.resource-header{padding:38px 0 24px;border-bottom:1px solid var(--line);text-align:center}.resource-header h1{margin:0 0 10px;color:var(--text);font:600 clamp(36px,4vw,44px)/1.08 "Space Grotesk";letter-spacing:-.035em}.resource-description{margin:0 auto;color:var(--text);font-size:19px;line-height:1.4}.home-search{max-width:800px;margin:22px auto 16px;text-align:left}.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}.home-search-control{display:flex;gap:10px}.home-search input{flex:1;min-width:0;padding:14px 16px;color:var(--text);background:var(--surface);border:1px solid var(--line-strong);border-radius:var(--radius-sm);outline:none;font-size:15px;box-shadow:var(--shadow-sm)}.home-search input::placeholder{color:#8b9dab}.home-search input:focus{border-color:var(--brand);box-shadow:0 0 0 3px #176b871a}.resource-links{display:flex;flex-wrap:wrap;justify-content:center;gap:7px 24px;align-items:center}.resource-links a{padding:7px 0;color:var(--brand);border-bottom:1px solid transparent;font-size:13px}.resource-links a:hover{border-bottom-color:var(--brand)}.resource-summary{margin:16px 0 0;color:var(--muted);font:11px DM Mono}.resource-summary span{color:var(--line-strong);padding:0 4px}.section{padding:24px 0 80px}.section-heading{display:flex;justify-content:space-between;align-items:end;gap:20px;margin-bottom:24px}.section-heading h2,.panel h2{font:600 25px Space Grotesk;margin:0;letter-spacing:-.03em;color:var(--text)}.inline-link,.back-link{color:var(--brand);font:12px DM Mono}.inline-link:hover,.back-link:hover,.text-button:hover{text-decoration:underline}.disease-grid{display:grid;grid-template-columns:repeat(6,minmax(0,1fr));gap:12px}.disease-card{padding:22px 16px;min-height:210px;background:var(--surface);border:1px solid var(--line);border-radius:var(--radius-md);box-shadow:var(--shadow-sm);display:flex;flex-direction:column;transition:transform .2s,border-color .2s,box-shadow .2s}.disease-card:hover{transform:translateY(-4px);border-color:#96beca;box-shadow:var(--shadow-md)}.card-index,.row-number{color:var(--accent);font:11px DM Mono}.disease-card h3{font:600 18px/1.2 Space Grotesk;margin:35px 0 8px;color:var(--text);overflow-wrap:anywhere}.disease-card p{color:var(--text-secondary);font-size:12px;line-height:1.45;margin:0;flex:1}.disease-card .disease-note{min-height:35px}.card-footer{display:flex;justify-content:space-between;align-items:center;gap:7px;margin-top:18px;color:var(--muted);font:9px DM Mono}.effect-badge{display:inline-block;padding:4px 6px;color:#fff;background:var(--positive);border-radius:3px;font:600 10px DM Mono;letter-spacing:.04em}.effect-badge.or{background:var(--accent)}.feature-strip{border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding:42px 0;display:flex;align-items:center;justify-content:space-between;gap:30px}.feature-strip h2{max-width:400px;font:600 28px Space Grotesk;margin:0;color:var(--text)}.feature-stats{display:flex;gap:50px}.feature-stats span{display:grid;gap:8px}.feature-stats strong{font:600 18px Space Grotesk;color:var(--brand)}.feature-stats small{font:10px DM Mono;color:var(--muted)}.page-header{padding:42px 0 28px;text-align:center;border-bottom:1px solid var(--line)}.page-header.compact{padding-bottom:26px}.page-header>p:not(.kicker){margin:0 auto}.disease-list{border-top:1px solid var(--line)}.disease-row{display:grid;grid-template-columns:70px 1fr 52px;gap:20px;align-items:center;padding:24px 0;border-bottom:1px solid var(--line)}.row-title{display:flex;gap:15px;align-items:center}.row-title h2{font:600 25px Space Grotesk;margin:0;color:var(--text)}.row-main p{color:var(--text-secondary);margin:7px 0 10px}.row-main small,.row-main code,code{color:var(--muted);font:10px DM Mono}.arrow-button{width:42px;height:42px;border:1px solid var(--line-strong);border-radius:50%;display:grid;place-items:center;color:var(--brand);font-size:20px}.arrow-button:hover{border-color:var(--brand);background:var(--brand-soft)}.search-bar,.filter-strip{display:flex;gap:12px;align-items:end;padding:18px;margin-bottom:22px;background:var(--surface);border:1px solid var(--line);border-radius:var(--radius-md);box-shadow:var(--shadow-sm)}.search-bar label,.filter-strip label{display:grid;gap:7px;color:var(--text-secondary);font:10px DM Mono;flex:1}.search-bar input,.filter-strip input{width:100%;padding:12px;color:var(--text);background:#fbfcfd;border:1px solid var(--line-strong);border-radius:var(--radius-sm);outline:none}.search-bar input::placeholder,.filter-strip input::placeholder{color:#9aabb8}.search-bar input:focus,.filter-strip input:focus{border-color:var(--brand);box-shadow:0 0 0 3px #176b871a}.table-card,.panel{background:var(--surface);border:1px solid var(--line);border-radius:var(--radius-md);box-shadow:var(--shadow-sm);padding:24px;margin-bottom:20px}.table-toolbar{display:flex;justify-content:space-between;margin-bottom:16px;color:var(--text-secondary);font:12px DM Mono}.bounded-note{color:var(--accent);font:10px DM Mono}.exposure-table{overflow-x:auto}.table-head,.table-row{display:grid;grid-template-columns:2.2fr 1.05fr 1.15fr 1fr;gap:18px;align-items:center;min-width:750px}.table-head{padding:9px 0;color:var(--muted);font:10px DM Mono;text-transform:uppercase;border-bottom:1px solid var(--line)}.table-row{padding:14px 0;border-bottom:1px solid #e8eef2;font-size:12px;color:var(--text)}.table-row:last-child{border-bottom:0}.table-row>span{min-width:0}.table-row strong,.table-row small{display:block}.table-row small{margin-top:5px;color:var(--muted);font:10px DM Mono;white-space:normal}.table-row:hover{color:var(--brand);background:#fbfdfe}.arrow{color:var(--brand);font-size:18px}.state-message{min-height:100px;display:flex;align-items:center;gap:12px;padding:22px;border:1px dashed var(--line-strong);border-radius:var(--radius-md);color:var(--muted);font-size:13px;background:#ffffffa6}.state-message.error{border-color:#e0b5b5;color:var(--negative);background:#fff8f8}.state-icon{color:var(--brand);font:22px DM Mono}.error .state-icon{color:var(--negative)}.muted,.caveat{color:var(--muted);line-height:1.6;font-size:12px}.notice{padding:10px;color:var(--brand-strong);background:var(--brand-soft);border-radius:var(--radius-sm);font:11px DM Mono}.back-link{display:inline-block;padding-top:28px}.detail-hero{padding:30px 0 24px;text-align:center}.detail-hero>p{margin:0 auto}.id-chip{display:inline-block;padding:8px 10px;border:1px solid var(--line);border-radius:var(--radius-sm);color:var(--brand);margin-top:12px;background:var(--surface-accent)}.metric-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:12px;margin-bottom:20px}.metric-card{padding:19px;border:1px solid var(--line);border-radius:var(--radius-md);background:var(--surface);box-shadow:var(--shadow-sm);min-width:0}.metric-card strong{display:block;margin:12px 0 5px;overflow:hidden;text-overflow:ellipsis;color:var(--text);font:600 22px Space Grotesk}.metric-card small{color:var(--muted);font:10px DM Mono}.coverage-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:10px}.coverage-grid div{padding:15px;border:1px solid var(--line);border-radius:var(--radius-sm);display:grid;gap:8px;background:var(--surface-subtle)}.coverage-grid span{color:var(--muted);font:10px DM Mono}.evidence-hero{padding:30px 0 24px;display:grid;justify-items:center;gap:18px;text-align:center}.evidence-hero p{margin:0 auto}.hero-effect{display:grid;gap:7px;justify-items:center;color:var(--muted);font:10px DM Mono}.hero-effect .effect-badge{font-size:16px;padding:7px 11px}.chart-wrap{border-top:1px solid var(--line);padding-top:15px}.chart-actions{display:flex;justify-content:space-between;color:var(--muted);font:10px DM Mono}.text-button{border:0;background:none;color:var(--brand);font:10px DM Mono}.chart{height:280px}.tabs{display:flex;gap:4px;border-bottom:1px solid var(--line);margin:-24px -24px 20px;padding:0 24px}.tabs button{border:0;border-bottom:2px solid transparent;padding:16px 14px;color:var(--muted);background:none;font:11px DM Mono}.tabs button span{color:var(--accent)}.tabs button.active{color:var(--brand);border-bottom-color:var(--brand)}.evidence-columns{display:grid;grid-template-columns:1fr 1fr;gap:20px}.provenance{overflow:hidden;color:var(--muted);font:9px DM Mono;white-space:nowrap;text-overflow:ellipsis}.provenance code{color:var(--brand)}.caveat{border-left:2px solid var(--accent);padding-left:12px}.network-controls{flex-wrap:wrap}.network-controls label{flex:1 1 180px}.network-header{display:flex;justify-content:space-between;align-items:end;margin:34px 0 15px}.network-header h2{font:600 28px Space Grotesk;margin:8px 0;color:var(--text)}.network-frame{position:relative;height:590px;background:#f1f6f8;border:1px solid var(--line);border-radius:var(--radius-md);overflow:hidden}.sigma-canvas{position:absolute;top:0;right:0;bottom:0;left:0}.network-hint,.network-detail{position:absolute;left:20px;bottom:20px;max-width:calc(100% - 40px);padding:13px;background:#fffffff0;border:1px solid var(--line);border-radius:var(--radius-sm);box-shadow:var(--shadow-sm);display:grid;gap:5px;font-size:12px}.network-detail span{color:var(--accent);font:11px DM Mono}.copilot-page{max-width:760px;margin:0 auto;padding:72px 0;text-align:center}.copilot-page>p:not(.kicker){margin-left:auto;margin-right:auto}.copilot-page h1{margin-bottom:16px}.copilot-state{display:grid;grid-template-columns:auto 1fr auto;gap:5px 10px;padding:17px;border:1px solid #e5d2b4;border-radius:var(--radius-md);background:#fffaf3;margin:30px 0;text-align:left}.copilot-state small{grid-column:2;color:var(--muted);font:11px DM Mono}.copilot-state .text-button{grid-column:3;grid-row:1 / span 2;align-self:center}.copilot-state.is-connected{border-color:#b6d4c9;background:#f3fbf7}.copilot-state.is-offline{border-color:#e0b5b5;background:#fff8f8}.status-dot{width:8px;height:8px;margin-top:5px;border-radius:50%;background:var(--accent)}.is-connected .status-dot{background:var(--positive)}.is-offline .status-dot{background:var(--negative)}.report-request{margin:30px 0 20px;text-align:left}.report-preview-header,.report-result-heading{display:flex;justify-content:space-between;align-items:center;gap:18px}.report-preview-header .kicker{margin-bottom:0}.copilot-form{display:grid;grid-template-columns:1fr 1fr;gap:14px;margin:24px 0}.copilot-form label{display:grid;gap:7px;color:var(--text-secondary);font:10px DM Mono}.copilot-form select,.copilot-form input{width:100%;padding:12px;color:var(--text);background:#fbfcfd;border:1px solid var(--line-strong);border-radius:var(--radius-sm);outline:none}.copilot-form select:focus,.copilot-form input:focus{border-color:var(--brand);box-shadow:0 0 0 3px #176b871a}.exposure-search{grid-column:1 / -1}.exposure-search>div{display:flex;gap:8px}.exposure-search input{flex:1}.report-result{padding:28px;margin:20px 0;background:var(--surface);border:1px solid var(--line);border-radius:var(--radius-md);box-shadow:var(--shadow-sm);text-align:left}.report-progress{display:flex;align-items:center;gap:8px;margin-top:14px;color:var(--text-secondary);font:11px DM Mono}.report-progress-panel{margin-top:18px;padding:16px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-subtle);text-align:left}.report-progress-panel p{margin:10px 0 4px;color:var(--text-secondary);font-size:13px;line-height:1.5}.report-progress-panel>small{color:var(--muted);font:10px DM Mono}.report-progress-snapshot{display:flex;justify-content:space-between;gap:12px;margin-top:14px;padding-top:12px;border-top:1px solid var(--line);color:var(--brand);font:11px DM Mono}.report-progress-snapshot span{color:var(--muted)}.report-token-stream{margin-top:14px;padding:14px;border-left:3px solid var(--brand);background:var(--surface)}.report-token-stream-heading{display:flex;justify-content:space-between;gap:12px;color:var(--brand);font:11px DM Mono}.report-token-stream-heading span{color:var(--muted)}.report-token-stream p{margin:10px 0 0;white-space:pre-wrap;color:var(--text-secondary);font-size:13px;line-height:1.65}.report-stage-list{display:flex;flex-wrap:wrap;gap:6px;margin-top:14px}.report-stage-list span{padding:5px 8px;border:1px solid var(--line);border-radius:999px;color:var(--muted);font:10px DM Mono}.report-stage-list span.active{border-color:var(--brand);color:var(--brand);background:#eef8fb}.report-stage-list span.done{color:var(--positive);border-color:#b6d4c9}.report-result-heading h2{margin:0;font:600 26px Space Grotesk;color:var(--text)}.verification-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:10px;margin:24px 0}.verification-grid span{display:grid;gap:6px;padding:14px;background:var(--surface-subtle);border:1px solid var(--line);border-radius:var(--radius-sm)}.verification-grid strong{color:var(--brand);font:600 14px Space Grotesk;overflow-wrap:anywhere}.verification-grid small,.report-sections small{color:var(--muted);font:10px DM Mono}.report-sections{display:grid;grid-template-columns:repeat(3,1fr);gap:10px}.report-sections article{padding:15px;border:1px solid var(--line);border-radius:var(--radius-sm);background:#fbfcfd}.report-sections h3,.report-copy h3{margin:0 0 8px;color:var(--text);font:600 15px Space Grotesk}.report-sections p,.report-copy p,.report-copy li{color:var(--text-secondary);font-size:13px;line-height:1.6}.report-copy{margin-top:22px;padding-top:18px;border-top:1px solid var(--line)}.report-copy ul{padding-left:20px;margin:8px 0 0}.report-copy code{overflow-wrap:anywhere}.reference-list a{color:var(--brand);text-decoration:underline;text-underline-offset:2px}.reference-list small{color:var(--muted);font:10px DM Mono}.finding-list strong{margin-right:5px;color:var(--brand);font:10px DM Mono;text-transform:uppercase}.finding-list .finding-warn strong,.finding-list .finding-fail strong{color:var(--accent)}.numeric-claim-list strong{color:var(--text)}.report-preview{padding:22px;margin:0 0 28px;border:1px solid var(--line);border-radius:var(--radius-md);background:var(--surface);box-shadow:var(--shadow-sm)}.report-preview-header{display:flex;justify-content:space-between;align-items:center;gap:12px}.report-preview-header .kicker{margin:0}.report-preview h2{margin:20px 0 16px;font:600 22px Space Grotesk;color:var(--text)}.report-preview-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:10px}.report-preview-grid span{display:grid;gap:7px;padding:13px;border:1px solid var(--line);border-radius:var(--radius-sm);background:var(--surface-subtle)}.report-preview-grid strong{font-size:12px}.report-preview-grid small{color:var(--muted);font:10px/1.5 DM Mono}@media(max-width:1024px){.topbar{gap:20px}.main-nav{gap:12px}.version-pill{display:none}.disease-grid{grid-template-columns:repeat(3,minmax(0,1fr))}}@media(max-width:650px){.topbar{height:64px;padding:0 20px}.menu-toggle{display:block}.main-nav{display:none;position:absolute;left:0;right:0;top:64px;padding:15px 20px;background:var(--surface);border-bottom:1px solid var(--line);box-shadow:var(--shadow-md);flex-direction:column;align-items:start}.main-nav.is-open{display:flex}.page-wrap{width:min(100% - 28px,1290px)}.site-footer{width:calc(100% - 28px);display:grid;gap:8px;margin-top:55px}.resource-header{padding:32px 0 22px}.resource-header h1{font-size:38px}.resource-description{font-size:18px}.home-search-control{display:grid;grid-template-columns:1fr}.home-search-control .button{width:100%}.resource-links{gap:4px 17px}.resource-summary{line-height:1.6}.disease-grid{grid-template-columns:1fr}.section-heading,.feature-strip,.evidence-hero,.network-header{display:block}.section-heading .inline-link{display:inline-block;margin-top:14px}.feature-stats{margin-top:30px;gap:22px;flex-wrap:wrap}.page-header{padding:34px 0 24px}.page-header h1,.detail-hero h1,.evidence-hero h1{font-size:38px}.disease-row{grid-template-columns:31px 1fr 35px;gap:8px}.row-title{align-items:start;flex-direction:column;gap:8px}.row-title h2{font-size:20px}.search-bar,.filter-strip{display:grid;grid-template-columns:1fr;align-items:stretch}.metric-grid{grid-template-columns:repeat(2,1fr)}.coverage-grid,.evidence-columns,.report-preview-grid{grid-template-columns:1fr}.copilot-state{grid-template-columns:auto 1fr}.copilot-state .text-button{grid-column:2;grid-row:auto;justify-self:start;margin-top:6px}.copilot-form,.report-sections,.verification-grid{grid-template-columns:1fr}.report-result{padding:16px}.report-result-heading{align-items:start;flex-direction:column}.panel,.table-card{padding:16px}.tabs{margin:-16px -16px 16px;padding:0 12px;overflow-x:auto}.hero-effect{margin-top:25px}.network-frame{height:460px}.network-controls .button{width:100%}.chart{height:230px}.chart-actions{gap:10px;align-items:start;flex-direction:column}}